— Publications

Selected Publications

  • bechstedt-2012

    Doublecortin recognizes the 13-protofilament microtubule cooperatively and tracks microtubule ends.

    Bechstedt S, Brouhard GJ. (2012) Developmental Cell. 23(1): 181-92.

    PMID: 22727374
  • wieczorek-2015

    Microtubule-associated proteins control the kinetics of microtubule nucleation.

    Wieczorek M, Bechstedt S, Chaaban S, Brouhard GJ. (2015) Nature Cell Biology. 17(7): 907-16.

    PMID: 26098575
  • bechstedt-2014-currbiol

    Doublecortin recognizes the longitudinal curvature of the microtubule end and lattice.

    Bechstedt S, Lu K, Brouhard GJ. (2014) Current Biology. 24(20): 2366-75.

    PMID: 25283777
  • JCB-2014

    The contribution of αβ-tubulin curvature to microtubule dynamics.

    Brouhard GJ, Rice LM. (2014) Journal of Cell Biology 207(3): 323-34.

    PMID: 25385183
  • wieczorek-2013

    Macromolecular crowding pushes catalyzed microtubule growth to near the theoretical limit.

    Wieczorek M, Chaaban S, Brouhard GJ. (2013) Cellular and Molecular Bioengineering 6(4): 383-392.

    DOI: 10.1007/s12195-013-0292-9
  • brouhard-2010-METHODS

    Quality control in single-molecule studies of kinesins and microtubule-associated proteins.

    Brouhard GJ. (2010) Methods Cell Biol. 97: 497-506.

    PMID: 20719287

2015

  • bechstedt-2014-currbiol

    The contribution of ab-tubulin curvature to microtubule dynamics.

    Brouhard GJ, Rice LM. Journal of Cell Biology. Nov 10;207(3):323-34.

    PMID: 25385183

2014

  • bechstedt-2014-currbiol

    The contribution of ab-tubulin curvature to microtubule dynamics.

    Brouhard GJ, Rice LM. Journal of Cell Biology. Nov 10;207(3):323-34.

    PMID: 25385183
  • bechstedt-2014-currbiol

    Doublecortin Recognizes the Longitudinal Curvature of the Microtubule End and Lattice.

    Bechstedt S, Lu K, Brouhard GJ. Current Biology. 2014 Oct 1. pii: S0960-9822(14)01052-5.

    PMID: 25283777
  • khazei-2014-jbc

    Collapsin Response Mediator Protein 4 Regulates Growth Cone Dynamics through the Actin and Microtubule Cytoskeleton.

    Khazaei MR, Girouard MP, Alchini R, Ong Tone S, Shimada T, Bechstedt S, Cowan M, Guillet D, Wiseman PW, Brouhard G, Cloutier JF, Fournier AE. Journal of Biological Chemistry. 2014 Oct 24;289(43):30133-43.

    PMID: 25225289
  • noujaim-2014-plos1

    Microtubules accelerate the kinase activity of Aurora-B by a reduction in dimensionality.

    Noujaim M, Bechstedt S, Wieczorek M, Brouhard GJ. PLoS One. 2014 Feb 3;9(2):e86786

    PMID: 24498282

2013

  • wieczorek-2013

    Macromolecular crowding pushes catalyzed microtubule growth to near the theoretical limit.

    Wieczorek M, Chaaban S, Brouhard GJ. (2013) Cellular and Molecular Bioengineering 6: 383-392.

    DOI: 10.1007/s12195-013-0292-9
  • bechstedt-2013-devcell

    Motors and MAPs collaborate to size up microtubules.

    Bechstedt S, Brouhard GJ. Developmental Cell 2013; ed: pp.

    PMID: 23906062
  • bechstedt-2013-methods

    Fluorescence-based assays for microtubule structure.

    Bechstedt S, Brouhard GJ. Methods in Cell Biology 2013; ed: pp.

    PMID: 23973082
  • brandao2013

    Measuring ligand-receptor binding kinetics and dynamics using k-space image correlation spectroscopy.

    Brandão HB, Sangji H, Pandžić E, Bechstedt S, Brouhard GJ, Wiseman PW. Methods 2013; ed: pp.

    PMID: 23938869
  • amron2013

    Polymicrogyria with dysmorphic basal ganglia? Think tubulin!

    Amrom D, Tanyalçin I, Verhelst H, Deconinck N, Brouhard G, Décarie JC, Vanderhasselt T, Das S, Hamdan F, Lissens W, Michaud J, Jansen A. Clinical Genetics 2013; ed: pp.

    PMID: 23495813

2012

  • bechstedt-2012

    Doublecortin recognizes the 13-protofilament microtubule cooperatively and tracks microtubule ends.

    Bechstedt S, Brouhard GJ. Developmental Cell 2012; ed: pp.

    PMID: 22727374
  • brouhard-2012

    Microtubules: sizing up the GTP cap.

    Brouhard G, Sept D. Current Biology 2012; ed: pp.

    PMID: 23017994

2011

  • bechstedt-2011

    Variations on the single-molecule assay for microtubule-associated proteins and kinesins.

    Bechstedt S, Wieczorek M, Noujaim M, Brouhard GJ. Methods Mol Biol. 2011;777:167-76.

    PMID: 21773928
  • widlund-PNAS

    XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region.

    Widlund PO, Stear JH, Pozniakovsky A, Zanic M, Reber S, Brouhard GJ, Hyman AA, Howard J. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2741-6.

    PMID: 21282620

2010

  • brouhard-2010-METHODS

    Quality control in single-molecule studies of kinesins and microtubule-associated proteins.

    Brouhard GJ.Methods Cell Biol. 2010;97:497-506.

    PMID: 20719287
  • al-bassam-2010

    CLASP promotes microtubule rescue by recruiting tubulin dimers to the microtubule.

    Al-Bassam J, Kim H, Brouhard G, van Oijen A, Harrison SC, Chang F. Dev Cell. 2010 Aug 17;19(2):245-58.

    PMID: 20708587
  • brouhard-2010-CurrentBiol

    Motor proteins: kinesins influence each other through load.

    Brouhard GJ. Curr Biol. 2010 May 25;20(10):R448-50.

    PMID: 20504755

Postdoctoral Publications

  • brouhard-Cell-XMAP215-2008

    XMAP215 is a processive microtubule polymerase.

    Brouhard GJ, Stear JH, Noetzel TL, Al-Bassam J, Kinoshita K, Harrison SC, Howard J, Hyman AA. Cell. 2008 Jan 11;132(1):79-88.

    PMID: 18191222
  • helenius-2006-NATURE

    The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends.

    Helenius J, Brouhard G, Kalaidzidis Y, Diez S, Howard J. Nature. 2006 May 4;441(7089):115-9.

    PMID: 16672973
  • gell-2010-Methods

    Microtubule dynamics reconstituted in vitro and imaged by single-molecule fluorescence microscopy.

    Gell C, Bormuth V, Brouhard GJ, Cohen DN, Diez S, Friel CT, Helenius J, Nitzsche B, Petzold H, Ribbe J, Schäffer E, Stear JH, Trushko A, Varga V, Widlund PO, Zanic M, Howard J. Methods Cell Biol. 2010;95:221-45. Review.

    PMID: 20466138
  • schroeter-DEV

    Dynamics of zebrafish somitogenesis.

    Schröter C, Herrgen L, Cardona A, Brouhard GJ, Feldman B, Oates AC. Dev Dyn. 2008 Mar;237(3):545-53.

    PMID: 18265021

Ph.D. Publications

  • Microtubule movements on the arms of mitotic chromosomes: polar ejection forces quantified in vitro.

    Brouhard GJ, Hunt AJ. Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13903-8.

    PMID: 16174726
  • Advanced optical tweezers for the study of cellular and molecular biomechanics.

    Brouhard GJ, Schek HT 3rd, Hunt AJ. IEEE Trans Biomed Eng. 2003 Jan;50(1):121-5.

    PMID: 12617534